How many people? 155,000 Americans lose their lives to lung cancer each year.
The #1 killer. Lung cancer is the leading cancer killer of both men and women in the U.S. (second only to heart disease in overall cause of death)
Research funding needed. Lung cancer receives only $1,831 in federal research funds per death, compared to $4,582 for colorectal cancer and $13,406 for breast cancer.
Not just a “smokers’s disease.” Around 70% of lung cancer victims are never-smokers (100 or fewer cigarettes smoked over a lifetime1).
Women at greater risk. Lung cancer is the leading cause of cancer death in women, killing more women each year than breast cancer, uterine cancer, and ovarian cancer combined. Two-thirds of never-smokers who develop lung cancer are women.
Lung cancer currently has only a 5-year overall survival rate of 5-20%, shockingly low compared to the next three most common cancers (breast, prostate and colon), which now have 5-year survival rates approaching 80 – 90%, thanks to research funding.
Lack of early detection. 41% of patients diagnosed with non-small cell lung cancer (NSCLC) are not diagnosed until Stage IV.1
EGFR-Positive Lung Cancer
Around 15% of all lung cancer patients in the U.S. are diagnosed with EGFR-positive (EGFR+) lung cancer, with prevalence among people of Eastern Asian descent much higher, between 35 – 50%.
Never-smokers. Lung cancers in non-smokers and never-smokers are far more likely to express the EGFR+ mutation.
Populations at greatest risk. EGFR+ is more common among: never-smokers and non-smokers; women than men; people of East Asian heritage; Caucasians than African Americans; young adults. (Roughly 50% of young adults with lung cancer have EGFR mutations.)
Lovly, C., L. Horn, W. Pao. 2015. EGFR in Non-Small Cell Lung Cancer (NSCLC). My Cancer Genome https://www.mycancergenome.org/content/disease/lung-cancer/egfr
Zhu QG, Zhang SM, Ding XX, He B, Zhang HQ. Driver genes in non-small cell lung cancer: Characteristics, detection methods, and targeted therapies. Oncotarget. 2017;8(34):57680-57692.
* Other sources of statistics include: American Cancer Society, National Cancer Institute.